|
KMID : 0360220210620040472
|
|
Journal of the Korean Ophthalmological Society
2021 Volume.62 No. 4 p.472 ~ p.478
|
|
|
Clinical Manifestations of Fungal Keratitis Following Penetrating Keratoplasty
|
|
Park Do-Hee
Nam Jeoung-Woo
Yoon Hyeon-Jeong
Yoon Kyung-Chul
|
|
|
Abstract
|
|
|
Purpose: We evaluated the clinical manifestations and risk factors of fungal keratitis after penetrating keratoplasty (PKP).
Methods: Eighteen patients who experienced fungal keratitis after PKP between January 2005 and January 2020 were includedin this retrospective study. Clinical characteristics including sex, age, underlying disease, indication for PKP, symptom duration,visual acuity, graft state before infection, suture-related problems, size of epithelial defect, depth of infiltration, presence of hypopyon,use of eyedrops before infection, and the results of microbiological tests were analyzed. Patients were classified into thetreatment success or failure group, and the risk factors were evaluated accordingly.
Results: The mean age at diagnosis was 63.94 ± 15.53 years. Fungal infection occurred a mean of 55.31 ± 44.72 months afterPKP. The mean symptom duration was 10.33 ± 7.36 days. Of the 18 patients, 5 (27.8%) and 13 (72.2%) were in the treatmentsuccess and failure groups, respectively. Of the treatment failure group, seven patients (38.9%) underwent surgicalmanagement. The graft state before infection, symptom duration, and size of epithelial defects had significant correlations withtreatment failure (all p < 0.05). Multivariate analysis identified graft state (p = 0.046) as a significant risk factor for treatmentfailure.
Conclusions: Graft state before infection, symptom duration, and size of epithelial defects were associated with the prognosis offungal keratitis after PKP. Graft state before infection was a significant risk factor for treatment failure.
|
|
|
KEYWORD
|
|
|
Fungal infection, Fungal keratitis, Graft state, Penetrating keratoplasty
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
  
|
|